The Role Of Medical-grade DMSO gel In Treatment Of Scleroderma

Scleroderma is a long-lasting rheumatic disease or connective tissue disorder characterized by consequent tightening and hardening of the skin followed by other tissues and internal organs which play a crucial role in the sustenance of human life.

The origin of the word “scleroderma” can be traced to ancient greek, where: “sclero” stands for hard, and “derma” refers to skin.

It occurs due to the malfunctioning of the auto-immune system, which stimulates the body to overproduce the protein collagen, which has no established cure till now.

This condition is highly prevalent in women ranging between the age group of 25-55. Although it is recognized not to be contagious, infectious or malignant, however, the severity and the outcome can vary, making it life-threatening.

However, effective management using Medical-grade DMSO can help maintain functionality while reducing the damage caused.

Causes: Despite advances in the medical field, we haven’t yet been able to pinpoint the exact cause behind this condition. However, genetic predisposition and environmental factors certainly play a key role in leading to its manifestation.

Types: There are mainly two kinds – Localized scleroderma and systemic scleroderma.

• Localized Scleroderma: This is the type that is primarily restricted to the skin. In severe cases, it impacts the muscles and tissues which is called subcutaneous localized scleroderma. It can be majorly spotted in children. It happens in 2 forms :

1.  Morphea – In this case darker and lighter shade patches are seen spread across the normal skin which might have mild pain, itchiness.
2. Linear – This causes a band or straight-line streak of thickened skin mostly in arms and limbs which can limit bone growth in children.

• Systemic Scleroderma: It is more severe as it affects the blood circulation and the internal organs thus proving fatal to life. There are several subtypes according to the tissues affected, but the major ones are :

1. Limited: It is the more subtle forms that take a longer time for the health to degrade. It can be managed easily as it starts by affecting the skin of the hand, feet, skin and lower arm and legs.
2. Diffuse: It is more serious as a larger area is affected which deteriorates rapidly causing unbearable pain. It expands to cease the functionalities of the lungs, blood vessels and the food tract.

Treatment with Medical- grade DMSO gel:

Although many treatments such as the use of UV light, immunosuppressants, BP medication have been streamlined aiming to relieve the symptoms, minimize disabilities and improve patient wellbeing, however therapy with medical-grade DMSO has proved to have the most effect.

Topical application of 60% concentration Medical-grade DMSO in the affected region improves the conditions of patients. Well-known as an

anti-inflammatory agent, it reduces the associated swelling. Also, it helps in improving the blood circulation across the body that helps to loosen the skin.

Extensive studies recently conducted on female scleroderma patients falling between the ages of 25-55 has given major insight. They were regularly administered with a mixture of 60% concentration Medical-grade DMSO with clean water for over one month. Along with the oral administration, topical application of DMSO gel was simultaneously continued. A report taken after a considerable period showed positive results. There was a drastic reduction in tightening of the skin.  DMSO gel increased blood flow to the skin that improved in restoring normal elasticity and softness along with muting the pain. However, tests conducted with lower concentrations of about 15 % bring no noticeable changes, which indicates that lower concentrations don’t act up to standards hence are not advisable for treatment.

Medical-grade DMSO gel is an effective, low-cost solution which, because of its diverse therapeutic properties, can help manage the condition effectively to improve overall well-being.

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